Search on: FAMILIAL SPASTIC PARAPARESIS, HTLV-1-ASSOCIATED 
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Descriptor English:   Paraparesis, Tropical Spastic 
Descriptor Spanish:   Paraparesia Espástica Tropical 
Descriptor Portuguese:   Paraparesia Espástica Tropical 
Synonyms English:   Familial Spastic Paraparesis, Htlv 1 Associated
Familial Spastic Paraparesis, Htlv-1-Associated
HTLV I Associated Myelopathies
HTLV I Associated Myelopathy
HTLV I Associated Myelopathy Tropical Spastic Paraparesis
HTLV-I-Associated Myelopathies
HTLV-I-Associated Myelopathy
HTLV-I-Associated Myelopathy-Tropical Spastic Paraparesis
Htlv-1-Associated Myelopathies
Htlv-1-Associated Myelopathy
Human T Lymphotropic Virus Type 1 Associated Myelopathy
Human T-Lymphotropic Virus Type 1 Associated Myelopathy
Myelopathies, HTLV I Associated
Myelopathies, HTLV-I-Associated
Myelopathies, Htlv-1-Associated
Myelopathy, HTLV-I-Associated
Myelopathy, Htlv 1 Associated
Myelopathy, Htlv-1-Associated
Myelopathy, Human T Lymphotropic Virus Type 1 Associated
Myelopathy, Human T-Lymphotropic Virus Type 1 Associated
Parapareses, Tropical Spastic
Paraplegia, Tropical Spastic
Paraplegias, Tropical Spastic
Spastic Parapareses, Tropical
Spastic Paraparesis, Tropical
Spastic Paraplegia, Tropical
Spastic Paraplegias, Tropical
Tropical Spastic Parapareses
Tropical Spastic Paraparesis
Tropical Spastic Paraplegia
Tropical Spastic Paraplegias  
Tree Number:   C01.207.618.500
C01.925.782.815.200.470.710
C10.228.228.618.500
C10.228.854.525.700
Definition English:   A subacute paralytic myeloneuropathy occurring endemically in tropical areas such as the Caribbean, Colombia, India, and Africa, as well as in the southwestern region of Japan; associated with infection by HUMAN T-CELL LEUKEMIA VIRUS I. Clinical manifestations include a slowly progressive spastic weakness of the legs, increased reflexes, Babinski signs, incontinence, and loss of vibratory and position sensation. On pathologic examination inflammatory, demyelination, and necrotic lesions may be found in the spinal cord. (Adams et al., Principles of Neurology, 6th ed, p1239) 
History Note English:   1989 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
TM transmission UR urine
VE veterinary VI virology
Record Number:   23795 
Unique Identifier:   D015493 

Occurrence in VHL: 		 

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